Article
Pathological phenotypes of astrocytes in Alzheimer's disease.
Experimental & molecular medicine - 1 Feb 2024
Kim Junhyung, Yoo Ik Dong, Lim Jaejoon, Moon Jong-Seok
Abstract excerpt
Astrocytes are involved in various processes in the central nervous system (CNS). As the most abundant cell type in the CNS, astrocytes play an essential role in neuronal maintenance and support, synaptic activity, neuronal metabolism, and amyloid-beta (Aβ) clearance. Alzheimer's disease (AD) is a neurodegenerative disorder associated with cognitive and behavioral impairment. The transformation of astrocytes is...
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