Article

TRANSIENT ALTERATIONS IN THALAMO-CEREBELLAR FUNCTIONAL CONNECTIVITY IN PREMANIFEST HUNTINGTON’S DISEASE

2025-01-15

Abstract excerpt

<h4>Background</h4> There are no disease modifying therapies for Huntington’s disease (HD), a rare but fatal genetic neurodegenerative condition. To develop and test new management strategies, a better understanding of the mechanisms underlying HD progression is needed. Aberrant changes in thalamo-cortical and striato-cerebellar circuitry have been observed in asymptomatic HD, along with transient enlargement of t...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9327706d-8fa9-5736-aa0e-873efead7fff
DOI: 10.1101/2025.01.15.25320232

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

TRANSIENT ALTERATIONS IN THALAMO-CEREBELLAR FUNCTIONAL CONNECTIVITY IN PREMANIFEST HUNTINGTON’S DISEASEDOI 10.1101/2025.01.15.25320232Read

Timing of selective basal ganglia white matter loss in Huntington’s diseaseSemantic proximity Read

Resting-State fMRI reveals Longitudinal Alterations in Brain Network Connectivity in a Mouse Model of Huntington’s DiseaseSemantic proximity Read

Network Dysconnection of Striatum and Default Mode Network Underpins Temporal Dynamics of Depression in Premanifest Huntington’s DiseaseSemantic proximity Read

Biological and clinical manifestations of Huntington's disease in the longitudinal TRACK-HD study: cross-sectional analysis of baseline data.Semantic proximity Read

Childhood to Adult Neurodevelopment in Gene-Expanded Huntington’s Disease (ChANGE-HD) study protocol: A Prospective Longitudinal Neurodevelopmental Study of Huntington’s DiseaseSemantic proximity Read

Impaired cortico-striatal functional connectivity in prodromal Huntington's DiseaseSemantic proximity Read

Whole-Brain Connectivity in a Large Study of Huntington's Disease Gene Mutation Carriers and Healthy ControlsSemantic proximity Read

Resting-State fMRI reveals Longitudinal Alterations in Brain Network Connectivity in the zQ175DN mouse Model of Huntington's DiseaseSemantic proximity Read

Prefrontal cortex white matter tracts in prodromal Huntington disease.Semantic proximity Read

Synaptic pathology in Huntington's disease: Beyond the corticostriatal pathwaySemantic proximity Read

Local synchronicity in dopamine-rich caudate nucleus influences Huntington's disease motor phenotype.Semantic proximity Read

Bioenergetic dysregulation in the basal ganglia and cerebellum of patients with premanifest and manifest Huntington’s diseaseSemantic proximity Read