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Article

Biological and clinical manifestations of Huntington's disease in the longitudinal TRACK-HD study: cross-sectional analysis of baseline data.

The Lancet. Neurology - 1 Sept 2009

Tabrizi Sarah J, Langbehn Douglas R, Leavitt Blair R, Roos Raymund Ac, Durr Alexandra, Craufurd David, Kennard Christopher, Hicks Stephen L, Fox Nick C, Scahill Rachael I, Borowsky Beth, Tobin Allan J, Rosas H Diana, Johnson Hans, Reilmann Ralf, Landwehrmeyer Bernhard, Stout Julie C

Abstract excerpt

BACKGROUND: Huntington's disease (HD) is an autosomal dominant, fully penetrant, neurodegenerative disease that most commonly affects adults in mid-life. Our aim was to identify sensitive and reliable biomarkers in premanifest carriers of mutated HTT and in individuals with early HD that could pr...

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Identifiers

PMID: 19646924
DOI: 10.1016/S1474-4422(09)70170-X
PMCID: PMC3725974

Genes

HTT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19646924-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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