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Childhood to Adult Neurodevelopment in Gene-Expanded Huntington’s Disease (ChANGE-HD) study protocol: A Prospective Longitudinal Neurodevelopmental Study of Huntington’s Disease

2025-10-24

Abstract excerpt

<h4>ABSTRACT</h4> Although adult Huntington’s disease (HD) studies have significantly advanced our understanding of the course of degeneration, they may underrepresent critical neurodevelopmental aspects of the disease. Significant gaps remain in understanding how mutant huntingtin affects early neurodevelopment, its long-term impact, as well as potential implications for treatment outcomes. The Childhood to Adul...

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Literature Corpus work: 7f276571-b1d1-5678-96ce-18ea8e744c82
DOI: 10.1101/2025.10.22.25338583

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