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Article

Prefrontal cortex white matter tracts in prodromal Huntington disease.

Human brain mapping - 1 Oct 2015

Matsui Joy T, Vaidya Jatin G, Wassermann Demian, Kim Regina Eunyoung, Magnotta Vincent A, Johnson Hans J, Paulsen Jane S

Abstract excerpt

Huntington disease (HD) is most widely known for its selective degeneration of striatal neurons but there is also growing evidence for white matter (WM) deterioration. The primary objective of this research was to conduct a large-scale analysis using multisite diffusion-weighted imaging (DWI) tractography data to quantify diffusivity properties along major prefrontal cortex WM tracts in prodromal HD. Fifteen...

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PMID: 26179962
DOI: 10.1002/hbm.22835
PMCID: PMC4583330

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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