Article

p75 Neurotrophin Receptor Shapes the Dynamics of Adult Hippocampal Neurogenesis in Alzheimer’s Disease

2025-09-16

Abstract excerpt

<h4>ABSTRACT</h4> Adult hippocampal neurogenesis is essential for cognitive flexibility and emotional resilience, and its disruption is strongly associated with Alzheimer’s disease, a disorder marked by cognitive decline and memory impairment. The p75 neurotrophin receptor regulates neuronal survival and plasticity, yet its contribution to adult hippocampal neurogenesis, especially under neurodegeneration, remain...

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Literature Corpus work: 6f27aaad-37de-5102-abea-be15bf3735d5
DOI: 10.1101/2025.09.11.675537

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