Article

Adult Human Neurogenesis in Alzheimer's Disease: Are New Neurons Being still Generated?

2024-10-14

Abstract excerpt

Alzheimer's disease is a progressive neurodegenerative disorder that disrupts the brain regions involved in memory and cognitive functions. This impairment ultimately results in severe deficits in memory, learning, reasoning, communication, and the ability to perform daily activities. Our research reveals a statistically significant decrease in the density of neural progenitor cells within the dentate gyrus o...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 60ba725a-adb8-5d6c-bf43-e9ad7466e406
DOI: 10.20944/preprints202410.1102.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Adult Human Neurogenesis in Alzheimer's Disease: Are New Neurons Being still Generated?DOI 10.20944/preprints202410.1102.v1Read

Neurogenesis, NSCs, pathogenesis and therapies for Alzheimer's disease.Semantic proximity Read

A roadmap to human hippocampal neurogenesis in adulthood, aging and AD.Semantic proximity Read

Early Changes in Hippocampal Neurogenesis in Transgenic Mouse Models for Alzheimer’s DiseaseSemantic proximity Read

Adult Neurogenesis, Neural Stem Cells and Alzheimers Disease: Developments, Limitations, Problems and PromisesSemantic proximity Read

p75 Neurotrophin Receptor Shapes the Dynamics of Adult Hippocampal Neurogenesis in Alzheimer's DiseaseSemantic proximity Read

Impaired neurogenesis is an early event in the etiology of familial Alzheimer's disease in transgenic mice.Semantic proximity Read

Alzheimer's-Type Amyloidosis in Transgenic Mice Impairs Survival of Newborn Neurons Derived from Adult Hippocampal NeurogenesisSemantic proximity Read

p75 Neurotrophin Receptor Shapes the Dynamics of Adult Hippocampal Neurogenesis in Alzheimer’s DiseaseSemantic proximity Read

Disruption of neurogenesis by amyloid beta-peptide, and perturbed neural progenitor cell homeostasis, in models of Alzheimer's disease.Semantic proximity Read

Characterization of adult hippocampal neurogenesis in the novel <i> App <sup>SAA</sup> </i> Knock-in Alzheimer’s disease mouse modelSemantic proximity Read

Enhancing Adult Neurogenesis Rescues Hippocampal Cognitive Functions in an Alzheimer’s Mouse ModelSemantic proximity Read

Impairments in neurogenesis are not tightly linked to depressive behavior in a transgenic mouse model of Alzheimer's disease.Semantic proximity Read