Article

Alzheimer’s Disease Mutations Disrupt Neural Stem Cell Fate and Early Brain Development

2025-03-16

Abstract excerpt

Alzheimer’s disease (AD) has been largely considered as an age-related disease, mainly affecting mature or aging adult brain. Recent studies show that AD-associated mutations could impair early life, even during neurodevelopment. However, due to the complex of AD mutations and neurodevelopmental regulations, how mutations in specific genes affect the origin of neurodevelopment is still largely under studied. In th...

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Literature Corpus work: 9aa80c86-26d0-52a8-9ec1-d36ab766c7ee
DOI: 10.1101/2025.03.16.643546

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