Article

Lysophosphatidic Acid-induced EGFR Transactivation Promotes Gastric Cancer DNA Replication Through Up-Regulation of Geminin

2020-09-22

Abstract excerpt

<title>Abstract</title> <p>BackgroundLysophosphatidic acid (LPA) is one of the simplest active phospholipid molecules. Binding to its receptors on the cell surface, LPA initiates various intracellular signal cascades, involving in numerous biological processes, such as cell proliferation, migration, and apoptosis. If abnormalities occur in the processes of LPA production, receptor expression or signal transductio...

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Literature Corpus work: 926e90ab-f452-5a4f-b211-11926495769d
DOI: 10.21203/rs.3.rs-79317/v1

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