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Article

Lysophosphatidic acid receptors in cancer pathobiology.

1 Mar 2014

Abstract excerpt

Lysophosphatidic acid (LPA) receptors (LPA₁ to LPA₆) are G protein-coupled transmembrane and mediate a variety of biological responses through the binding of LPA, such as cell proliferation, migration, morphogenesis and differentiation. Previously, high secretion levels of LPA were found in blood and ascites from patients with aggressive ovarian cancer. So far, numerical studies have demonstrated that LPA...

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PMID: 24194373
DOI: 10.14670/hh-29.313

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