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Article

MARK4 promotes the malignant phenotype of gastric cancer through the MAPK/ERK signaling pathway.

Pathology, research and practice - 1 Sept 2024

Ma Fubin, Yao Jibin, Niu Xingdong, Zhang Junrui, Shi Donghai, Da Mingxu

Abstract excerpt

BACKGROUND: Microtubule affinity regulating kinase 4 (MARK4), which is overexpressed in various tumors, is involved in the regulation of cell division, proliferation, migration, and the cell cycle, and has been considered a potential marker for cancer; however, its mechanism of action in gastric cancer (GC) remains unclear. This study aimed to investigate the role of MARK4 in the proliferation, migration, and...

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Share to Cell Movement
Share to Cell Proliferation
Share to Epithelial-Mesenchymal Transition

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to MAP Kinase Signaling System

Share to Neoplasm Invasiveness

Share to Protein Serine-Threonine Kinases

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Source

Identifiers

PMID: 39079384
DOI: 10.1016/j.prp.2024.155471

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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