Diverse effects of LPA receptors on cell motile activities of cancer cells

doi:10.3109/10799893.2013.876042

Article

Diverse effects of LPA receptors on cell motile activities of cancer cells

24 Jan 2014

Abstract excerpt

Lysophosphatidic acid (LPA) is a bioactive lipid that interacts with G protein-coupled transmembrane LPA receptors (LPA1 to LPA6). LPA mediates a variety of cellular responses in normal cells, including cell growth, motility, differentiation, morphogenesis, and prevention from apoptosis. Furthermore, LPA signaling via LPA receptors is involved in the pathogenesis of several diseases, including cancer. Cell...

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.