Article
Evaluation of the Role of LRRK2 Gene in Parkinson’s Disease in an East Indian Cohort
2012-01-01
Abstract excerpt
Leucine rich repeat kinase 2 (LRRK2) gene defects cause Parkinson's disease (PD). Recently, LRRK2 has also been shown by genome wide association (GWA) studies to be a susceptibility gene for the disease. In India mutations in LRRK2 is a rare cause of PD. We, therefore, genotyped 64 SNPs across LRRK2 in 161 control samples and finally studied 6 haplotype tagging SNPs for association-based study on 300 cases and 446...
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Identifiers and source
- Literature Corpus work
- 91a64adc-5ad1-5c53-b74b-36b1dc69810b
- DOI
- 10.1155/2012/895065