Article
Absence/rarity of commonly reported LRRK2 mutations in Indian Parkinson's disease patients.
Neuroscience letters - 1 Dec 2006
Punia Sohan, Behari Madhuri, Govindappa Shyla T, Swaminath Pazhayannur V, Jayaram Sachi, Goyal Vinay, Muthane Uday B, Juyal R C, Thelma B K
Abstract excerpt
Recent discovery of pathogenic mutations in the leucine-rich repeat kinase 2 (LRRK2) gene in Parkinson's disease (PD) patients in different ethnic groups have raised a hope of diagnostic screening and genetic counseling. We investigated the six most commonly reported mutations in LRRK2 gene among Indian PD patients, using PCR-RFLP method. Mutations G2019S, R1441C, R1441G, and R1441H were screened in 1012...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.