Article

Single-cell alternative polyadenylation analysis reveals mechanistic insights of COVID-19-associated neurological and psychiatric effects

2025-05-06

Abstract excerpt

<h4>Summary</h4> COVID-19 is associated with increased risks of neurological and psychiatric sequelae. Alternative polyadenylation (APA) is ubiquitous in human genes, resulting in mRNA diversity, and has been validated to play a pivotal regulatory role in the onset and progression of a variety of diseases, including viral infections. Here, we analyzed the APA usage across different cell types in frontal cortex ce...

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Literature Corpus work: 9193652f-d745-586b-a881-eeb62bb6a723
DOI: 10.1101/2025.05.02.651855

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