Article

Beyond polyA: scalable single-cell total RNA-seq unifies coding and non-coding transcriptomics

2025-08-10

Abstract excerpt

Non-coding RNAs represent a widespread and diverse layer of post-transcriptional regulation across cell types and states, yet much of their diversity remains uncharted at single-cell resolution. This gap stems from the limitations of widely used single-cell RNA-sequencing protocols, which focus on polyadenylated transcripts and miss many short or non-polyadenylated RNAs. Here, we adapted single-cell RNA-sequencing...

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Literature Corpus work: 13030932-8037-5b92-af9e-b12ac1e7c74e
DOI: 10.1101/2025.08.08.669394

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