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A compendium of conserved cleavage and polyadenylation events in mammalian genes.

Genome research - 1 Oct 2018

Wang Ruijia, Zheng Dinghai, Yehia Ghassan, Tian Bin

Abstract excerpt

Cleavage and polyadenylation is essential for 3' end processing of almost all eukaryotic mRNAs. Recent studies have shown widespread alternative cleavage and polyadenylation (APA) events leading to mRNA isoforms with different 3' UTRs and/or coding sequences. Here, we present a compendium of conserved cleavage and polyadenylation sites (PASs) in mammalian genes, based on approximately 1.2 billion 3' end...

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3' Untranslated Regions
Conserved Sequence
Organ Specificity
Polyadenylation
RNA, Long Noncoding

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sequence Analysis, RNA

Species Specificity

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PMID: 30143597
DOI: 10.1101/gr.237826.118
PMCID: PMC6169888

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