Article

Microglial states determine lesion dynamics in multiple sclerosis

2024-10-25

Abstract excerpt

<h4>Summary paragraph</h4> Multiple sclerosis (MS) is a neuroinflammatory disease of the central nervous system, characterized by demyelinating lesions 1 . Lesion expansion contributes to progression and increased disability, while remyelination can recover neurological deficits. However, mechanisms driving lesion dynamics are largely unclear, hindering the development of effective therapeutics. We propose that...

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Literature Corpus work: 913bdcb1-8748-5203-8d0c-e7ce98ee723f
DOI: 10.1101/2024.10.25.620251

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