Article

Foamy microglia link oxylipins to disease progression in multiple sclerosis

2024-10-21

Abstract excerpt

Multiple sclerosis (MS) is a neuroinflammatory disease characterized by expanding demyelinating lesions, leading to severe and irreversible disability. The mechanisms driving lesion expansion, however, remain poorly understood. Here, using a multi-omics approach, we identified foamy microglia as primary contributors to the molecular profile of lesions and disease progression in secondary progressive MS. Lesions wi...

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Literature Corpus work: b876e845-4f63-5928-b054-0237b2e540ad
DOI: 10.1101/2024.10.18.619040

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