Article

A single-cell multi-omics map of cell-type-specific mechanistic drivers of multiple sclerosis lesions

2023-05-09

Abstract excerpt

<title>Abstract</title> <p>Despite major progress in understanding the mechanisms in progressive multiple sclerosis (PMS), the underlying drivers of compartmentalized and sustained inflammation have not been resolved. To gain insights into the interplay between inter- and intra-cellular mechanisms and deconvolute the complex niche of lesion evolution, we have integrated single cell chromatin accessibility and tra...

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Literature Corpus work: 5b8f952c-0de8-53c6-b029-e3efa0315990
DOI: 10.21203/rs.3.rs-2845466/v1

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