Article

Human disease-specific cell signatures in non-lesional tissue in Multiple Sclerosis detected by single-cell and spatial transcriptomics

2023-12-20

Abstract excerpt

Recent investigations of cell type changes in Multiple Sclerosis (MS) using single-cell profiling methods have focused on active lesional and peri-lesional brain tissue, and have implicated a number of peripheral and central nervous system cell types. However, an important question is the extent to which so-called “normal-appearing” non-lesional tissue in individuals with MS accumulate changes over the lifespan. H...

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Literature Corpus work: af3c1d5b-a34b-56ba-86bc-030cebddd880
DOI: 10.1101/2023.12.20.572491

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