Article

Gene expression asymmetry in Parkinson’s Disease; Variation of CCT Gene Expression is Correlated with Hemisphere Specific Severity

2025-06-06

Abstract excerpt

<title>Abstract</title> Parkinson’s disease (PD) symptom onset is typically unilateral, which may be related to molecular differences underlying hemispheric vulnerability. Here we sampled prefrontal cortex bilaterally from people with PD and healthy controls and performed RNA-seq on neuronal nuclei to determine hemispheric and disease-related differences. Each brain hemisphere was related the side of symptom o...

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Literature Corpus work: 9057a06b-e826-5458-9140-ece1206cc7c4
DOI: 10.21203/rs.3.rs-6787061/v1

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