Article

Epigenetic contributions to hemisphere asymmetry in healthy brain, aging, and Parkinson’s disease

2019-10-07

Abstract excerpt

Hemispheric asymmetry in neuronal processes is a fundamental feature of the human brain and drives symptom lateralization in Parkinson’s disease (PD), but its molecular determinants are unknown. Here, we determine epigenetic differences involved in hemispheric asymmetry in the healthy and the PD brain. Neurons of the healthy brain exhibit numerous hemispheric differences in DNA methylation, which affect genes impl...

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Literature Corpus work: 22d57c12-0cba-5a30-b8a9-64c5305f58c5
DOI: 10.1101/794255

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