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Gene expression asymmetry in Parkinson’s Disease; variation of <i>CCT</i> and <i>BEX</i> gene expression levels are correlated with hemisphere specific severity

2024-07-04

Abstract excerpt

Parkinson’s Disease (PD) develops unilaterally, which may be related to brain hemispheric differences in gene expression. Here we measured bulk RNA-seq levels in neuronal nuclei obtained from prefrontal cortex postmortem brain samples from males and females with PD and from healthy controls. Left and right hemispheres from each brain were related the side of symptom onset and compared. We employed two a priori ap...

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Literature Corpus work
fe1bd7b2-05a8-5b5b-959b-0e0b8c3c0e50
DOI
10.1101/2024.07.02.601704
Open publication

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Gene expression asymmetry in Parkinson’s Disease; variation of <i>CCT</i> and <i>BEX</i> gene expression levels are correlated with hemisphere specific severityDOI 10.1101/2024.07.02.601704
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