Article

Cross-platform transcriptional profiling identifies common and distinct molecular pathologies in Lewy Body diseases

2021-04-22

Abstract excerpt

Parkinson’s disease (PD), Parkinson’s disease with dementia (PDD) and dementia with Lewy bodies (DLB) are three clinically, genetically and neuropathologically overlapping neurodegenerative diseases collectively known as the Lewy body diseases (LBDs). A variety of molecular mechanisms have been implicated in PD pathogenesis, but the mechanisms underlying PDD and DLB remain largely unknown, a knowledge gap that pre...

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Literature Corpus work: 7e707bbf-27c9-516b-830d-d10218bbd764
DOI: 10.1101/2021.04.22.440800

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