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Motor Functional Hierarchical Organization of Cerebrum and Its Underlying Genetic Architecture in Parkinson’s Disease

17 Jan 2025

Abstract excerpt

Hierarchy has been identified as a principle underlying the organization of human brain networks. However, it remains unclear how the network hierarchy is disrupted in Parkinson's disease (PD) motor symptoms and how it is modulated by the underlying genetic architecture. The aim of this study was to explore alterations in the motor functional hierarchical organization of the cerebrum and their underlying genetic...

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PMID: 39824632
DOI: 10.1523/jneurosci.1492-24.2024

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