Article

Transcriptomic signatures associated with regional cortical thickness changes in Parkinson’s disease

2020-06-19

Abstract excerpt

Cortical atrophy is a common manifestation in Parkinson’s disease, particularly in later disease stages. Here, we investigated patterns of cortical thickness using T1-weighted anatomical MRI data of 149 Parkinson’s disease patients and 369 controls. To elucidate the molecular underpinnings of cortical thickness changes in Parkinson’s disease, we performed an integrated analysis of brain-wide healthy transcriptomic...

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Literature Corpus work: 57f8fff2-5453-5714-99fc-642c76b1eae4
DOI: 10.1101/2020.06.19.158808

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