Article

Psoralen Enhances Direct Cardiac Reprogramming via PPARα Activation and Promotion of Mitochondrial Fission

2025-10-11

Abstract excerpt

<h4>ABSTRACT</h4> <h4>BACKGROUND</h4> Cell-based therapy is a promising strategy for heart repair and regeneration. However, its clinical application has been hampered by the low efficiency of cell direct reprogramming and the immature state of the inducing cells. Developing novel strategies to enhance direct reprogramming efficiency and yield mature functional cardiomyocytes remains a critical challenge. <h4>ME...

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Literature Corpus work: 8fe59a97-1f3b-5301-b72f-9a3ccf77dc5f
DOI: 10.1101/2025.10.08.681288

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