Article

Cardiomyocyte precursors generated by direct reprogramming and molecular beacon selection attenuate ventricular remodeling after experimental myocardial infarction

2022-03-31

Abstract excerpt

<title>Abstract</title> <p>Background Direct cardiac reprogramming is currently being investigated for the generation of cells with a true cardiomyocyte (CM) phenotype. Based on the original approach of cardiac transcription factor-induced reprogramming of fibroblasts into CM-like cells, various modifications of that strategy have been developed. However, they uniformly suffer from poor reprogramming efficacy an...

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Literature Corpus work: 657256d3-1746-57b8-87e8-8e1c485ef7bb
DOI: 10.21203/rs.3.rs-1449832/v1

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