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Article

Direct cardiac reprogramming: progress and challenges in basic biology and clinical applications.

Circulation research - 10 Apr 2015

Sadahiro Taketaro, Yamanaka Shinya, Ieda Masaki

Abstract excerpt

The discovery of induced pluripotent stem cells changed the field of regenerative medicine and inspired the technological development of direct reprogramming or the process by which one cell type is directly converted into another without reverting a stem cell state by overexpressing lineage-specific factors. Indeed, direct reprogramming has proven sufficient in yielding a diverse range of cell types from...

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Identifiers

PMID: 25858064
DOI: 10.1161/CIRCRESAHA.116.305374

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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