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Article

Nrf2 is required for structural and metabolic maturation of human induced pluripotent stem cell-derived cardiomyocytes

2021-01-08

Abstract excerpt

<h4>Background: </h4> Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) hold great promise for regenerative medicine and in vitro screening. Despite displaying key cardiomyocyte phenotypic characteristics, they more closely resemble fetal/neonatal cardiomyocytes and are still immature, these cells mainly rely on glucose as a substrate for metabolic energy, while mature cardiomyocytes mainly emp...

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Literature Corpus work
75bde72e-7bde-5c0d-abc6-72121d25ab6c
DOI
10.21203/rs.3.rs-140415/v1
Open publication

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