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Article

Direct Reprogramming—The Future of Cardiac Regeneration?

29 Jul 2015

Abstract excerpt

Today, the only available curative therapy for end stage congestive heart failure (CHF) is heart transplantation. This therapeutic option is strongly limited by declining numbers of available donor hearts and by restricted long-term performance of the transplanted graft. The disastrous prognosis for CHF with its restricted therapeutic options has led scientists to develop different concepts of alternative...

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PMID: 26230692
DOI: 10.3390/ijms160817368

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