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Leonurine (SCM-198) remodeled mitochondrial function and synergistically enhanced the myocardial repair potential of mesenchymal stem cells

2026-08-19

Abstract excerpt

<title>Abstract</title> <p> Myocardial ischemia/reperfusion (I/R) injury induces severe mitochondrial dysfunction, which restricts the therapeutic effectiveness of mesenchymal stem cell (MSC)-based cardiac repair. Leonurine, a natural alkaloid with established cardiovascular benefits, has demonstrated safety in Phase I clinical trials. This study was designed to explore whether leonurine enhances the myocardial...

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Literature Corpus work
55386902-9611-5cf3-81ce-d03c63d4e12c
DOI
10.21203/rs.3.rs-10014487/v1
Open publication

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Leonurine (SCM-198) remodeled mitochondrial function and synergistically enhanced the myocardial repair potential of mesenchymal stem cellsDOI 10.21203/rs.3.rs-10014487/v1
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