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Article

Genomic instability in patients with sex determination defects and germ cell cancer

2022-06-10

Abstract excerpt

The ability to transmit genetic information through generations depends on preservation of genome integrity. Genetic abnormalities affect cell differentiation, causing tissue specification defects and cancer. We addressed genomic instability in individuals with Differences of Sex Development (DSD), characterized by gonadal dysgenesis, infertility, high susceptibility for different types of cancer, especially Germ...

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Literature Corpus work
8f41baaf-2dfd-5cb8-9798-54d6b633c95d
DOI
10.1101/2022.06.08.495249
Open publication

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Genomic instability in patients with sex determination defects and germ cell cancerDOI 10.1101/2022.06.08.495249
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