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A Thiopurine-like Mutagenic Process Defines TGCT Subtypes

2025-06-16

Abstract excerpt

<title>Abstract</title> <p> Testicular germ cell tumors (TGCTs) are the most common malignancy in young men, exhibit a unique developmental origin and exceptional chemosensitivity. However, the molecular distinctions between TGCT subtypes remain poorly understood. Here we present a comprehensive genomic analysis of 252 treatment-naive primary TGCTs, integrating deep whole-genome sequencing with matched transcrip...

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Literature Corpus work
094fede5-0a77-5ff0-8a93-3c092f18c4c5
DOI
10.21203/rs.3.rs-6735635/v1
Open publication

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A Thiopurine-like Mutagenic Process Defines TGCT SubtypesDOI 10.21203/rs.3.rs-6735635/v1
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