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Article

Update on Recommendations for Cancer Screening and Surveillance in Children with Genomic Instability Disorders.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Nov 2024

Nakano Yoshiko, Kuiper Roland P, Nichols Kim E, Porter Christopher C, Lesmana Harry, Meade Julia, Kratz Christian P, Godley Lucy A, Maese Luke D, Achatz Maria Isabel, Khincha Payal P, Savage Sharon A, Doria Andrea S, Greer Mary-Louise C, Chang Vivian Y, Wang Lisa L, Plon Sharon E, Walsh Michael F

Abstract excerpt

Genomic instability disorders are characterized by DNA or chromosomal instability, resulting in various clinical manifestations, including developmental anomalies, immunodeficiency, and increased risk of developing cancers beginning in childhood. Many of these genomic instability disorders also present with exquisite sensitivity to anticancer treatments such as ionizing radiation and chemotherapy, which may...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39264246
DOI: 10.1158/1078-0432.CCR-24-1098
PMCID: PMC11705613

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