Article

Efficient and multiplexed somatic genome editing with Cas12a mice

2024-03-08

Abstract excerpt

<h4>ABSTRACT</h4> Somatic genome editing in mouse models has increased our understanding of the in vivo effects of genetic alterations in areas ranging from neuroscience to cancer biology and beyond. However, existing models are limited in their ability to create multiple targeted edits. Thus, our understanding of the complex genetic interactions that underlie development, homeostasis, and disease remains incomp...

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Literature Corpus work: 8ecf5a03-9204-5d6a-8d86-6590891f2ba5
DOI: 10.1101/2024.03.07.583774

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