Article

Multiplexed <i>in vivo</i> base editing identifies functional gene-variant-context interactions

2025-02-26

Abstract excerpt

Human genome sequencing efforts in healthy and diseased individuals continue to identify a broad spectrum of genetic variants associated with predisposition, progression, and therapeutic outcomes for diseases like cancer 1–6 . Insights derived from these studies have significant potential to guide clinical diagnoses and treatment decisions; however, the relative importance and functional impact of most genetic va...

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Literature Corpus work: 14ac2642-5da7-5bda-beaa-9ca82a999fa3
DOI: 10.1101/2025.02.23.639770

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