Article

Detecting the effect of genetic diversity on brain composition in an Alzheimer’s disease mouse model

2023-02-28

Abstract excerpt

Alzheimer’s disease (AD) is characterized by neurodegeneration, pathology accumulation, and progressive cognitive decline. There is significant variation in age at onset and severity of symptoms highlighting the importance of genetic diversity in the study of AD. To address this, we analyzed cell and pathology composition of 6- and 14-month-old AD-BXD mouse brains using the semi-automated workflow (QUINT); which w...

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Literature Corpus work: 8c5a41b4-ed90-5767-8b0d-a1da7d302ab9
DOI: 10.1101/2023.02.27.530226

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