Article

Integrated multimodal cell atlas of Alzheimer’s disease

2023-05-09

Abstract excerpt

Alzheimer’s disease (AD) is the most common cause of dementia in older adults. Neuropathological and imaging studies have demonstrated a progressive and stereotyped accumulation of protein aggregates, but the underlying molecular and cellular mechanisms driving AD progression and vulnerable cell populations affected by disease remain coarsely understood. The current study harnesses single cell and spatial genomics...

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Literature Corpus work: 80fad1cf-4d15-5afa-81ba-32841d57d450
DOI: 10.1101/2023.05.08.539485

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