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Article

Apolipoprotein E allele 4 effects on Single-Subject Gray Matter Networks in Mild Cognitive Impairment.

NeuroImage. Clinical - 1 Jan 2021

Sanabria-Diaz Gretel, Demonet Jean-Francois, Rodriguez-Herreros Borja, Draganski Bogdan, Kherif Ferath, Melie-Garcia Lester

Abstract excerpt

There is evidence that gray matter networks are disrupted in Mild Cognitive Impairment (MCI) and associated with cognitive impairment and faster disease progression. However, it remains unknown how these alterations are related to the presence of Apolipoprotein E isoform E4 (ApoE4), the most prominent genetic risk factor for late-onset Alzheimer's disease (AD). To investigate this topic at the individual level,...

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Identifiers

PMID: 34469849
DOI: 10.1016/j.nicl.2021.102799
PMCID: PMC8405842

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