Article

Reactive oxygen species-evoked endoplasmic reticulum stress mediates albumin load-induced epithelial-mesenchymal transition in podocytes

2025-11-13

Abstract excerpt

<title>Abstract</title> <p>Background Epithelial-mesenchymal transition (EMT) plays a significant role in cell migration and tissue fibrosis. Podocytes may undergo EMT after injury, leading to podocyte migration and detachment, which results ultimately in albuminuaria and renal fibrosis. The molecular mechanisms linking albuminuria to the progression of renal fibrosis is complex and not yet fully understood. Reac...

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Literature Corpus work: 8bc8cf02-abfc-588d-8c2b-9e5887341cca
DOI: 10.21203/rs.3.rs-8002591/v1

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