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Article

DsbA-L mediated renal tubulointerstitial fibrosis in UUO mice.

Nature communications - 18 Sept 2020

Li Xiaozhou, Pan Jian, Li Huiling, Li Guangdi, Liu Xiangfeng, Liu Bohao, He Zhibiao, Peng Zhengyu, Zhang Hongliang, Li Yijian, Xiang Xudong, Chai Xiangping, Yuan Yunchang, Zheng Peilin, Liu Feng, Zhang Dongshan

Abstract excerpt

Recent studies have reported that upregulation of disulfide-bond A oxidoreductase-like protein (DsbA-L) prevented lipid-induced renal injury in diabetic nephropathy (DN). However, the role and regulation of proximal tubular DsbA-L for renal tubulointerstitial fibrosis (TIF) remains unclear. In current study, we found that a proximal tubules-specific DsbA-L knockout mouse (PT-DsbA-L-KO) attenuated UUO-induced TIF,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32948751
DOI: 10.1038/s41467-020-18304-z
PMCID: PMC7501299

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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