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Article

Knockdown of RTN1A attenuates ER stress and kidney injury in albumin overload-induced nephropathy.

American journal of physiology. Renal physiology - 1 Mar 2016

Xiao Wenzhen, Fan Ying, Wang Niansong, Chuang Peter Y, Lee Kyung, He John Cijiang

Abstract excerpt

Our previous studies have suggested a critical role of reticulon (RTN)1A in mediating endoplasmic reticulum (ER) stress in kidney cells of animal models and humans with kidney diseases. A large body of evidence suggests that proteinuria itself can cause tubular cell injury leading to the progression of kidney disease. In the present study, we determined whether RTN1A mediates proteinuria-induced tubular cell...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26739891
DOI: 10.1152/ajprenal.00485.2015
PMCID: PMC4773829

Genes

RTN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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