Article
Dysfunction of the ER chaperone BiP accelerates the renal tubular injury.
Biochemical and biophysical research communications - 22 Feb 2008
Kimura Keita, Jin Hisayo, Ogawa Makoto, Aoe Tomohiko
Abstract excerpt
Tubular-interstitial injury plays a key role in the progression of chronic kidney disease. Although endoplasmic reticulum (ER) stress plays significant roles in the development of chronic diseases such as neurodegenerative disease, cardiomyopathy and diabetes mellitus, its pathophysiological role...
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