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Article

Modeling oxidative injury response in human kidney organoids

2021-08-24

Abstract excerpt

<title>Abstract</title> <p>BackgroundPersistent acute kidney injury (AKI) leads to tubular atrophy, kidney fibrosis, and, if severe enough, chronic kidney disease (CKD). A common feature of AKI is the generation of excessive reactive oxygen species (ROS) which damage cells and induce inflammation. MethodsHuman kidney organoids were treated with hemin, an iron-containing porphyrin derived from lysed red blood cell...

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Literature Corpus work
713526f8-2847-576f-863c-5f21e0cab16a
DOI
10.21203/rs.3.rs-826877/v1
Open publication

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Modeling oxidative injury response in human kidney organoidsDOI 10.21203/rs.3.rs-826877/v1
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