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Article

Proteomics characterization of cell model with renal fibrosis phenotype: osmotic stress as fibrosis triggering factor.

Journal of proteomics - 1 Mar 2011

Dihazi Hassan, Dihazi Gry Helene, Mueller Claudia, Lahrichi Loubna, Asif Abdul R, Bibi Asima, Eltoweissy Marwa, Vasko Radovan, Mueller Gerhard A

Abstract excerpt

Renal fibroblasts are thought to play a major role in the development of renal fibrosis (RF). The mechanisms leading to this renal alteration remain poorly understood. We performed differential proteomic analyses with two established fibroblast cell lines with RF phenotype to identify new molecular pathways associated with RF. Differential 2-DE combined with mass spectrometry analysis revealed the alteration of...

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Share to Electrophoresis, Gel, Two-Dimensional
Share to Endoplasmic Reticulum

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Fluorescent Antibody Technique, Indirect

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Source

Identifiers

PMID: 21118732
DOI: 10.1016/j.jprot.2010.11.007

Genes

CALR
HYOU1
PRDX1
PRDX2
PRDX6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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