Article

Tuft cells restrain pancreatic tumorigenesis through paracrine eicosanoid signaling

2019-12-20

Abstract excerpt

Despite numerous advances in our understanding of pancreatic ductal adenocarcinoma (PDA) genetics and biology, this disease is expected to become the second leading cause of cancer-related U.S. deaths within the next few years. Incomplete understanding of how it arises precludes development of early detection and interception strategies to improve therapeutic outcomes. Acinar to ductal metaplasia involving genesis...

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Literature Corpus work: 8ba2d338-a561-58e8-b97b-1ef41557af30
DOI: 10.1101/2019.12.19.882985

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