Article

Single-cell transcriptomics reveals a conserved metaplasia program in pancreatic injury

2021-04-11

Abstract excerpt

<h4>ABSTRACT</h4> <h4>BACKGROUND & AIMS</h4> Acinar to ductal metaplasia (ADM) occurs in the pancreas in response to tissue injury and is a potential precursor for adenocarcinoma. The goal of these studies was to define the populations arising from ADM, the associated transcriptional changes, and markers of disease progression. <h4>METHODS</h4> Acinar cells were lineage-traced with enhanced yellow fluorescent p...

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Literature Corpus work: 432f635f-c2d2-5468-83d6-0ae7e545d2a8
DOI: 10.1101/2021.04.09.439243

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