Back to search

Article

Rich polymorphic variants of alpha satellite 34mer higher order repeats in hg38 assembly of human chromosome Y

2019-09-13

Abstract excerpt

A challenging problem in human population genetics is related to the unique role of human Y chromosome, with properties that distinguish humans from other species. Centromeres in primate genomes are constituted of tandem repeats of ∼ 171 bp alpha satellite monomers, commonly organized into higher order repats (HORs). Because of gaps in DNA sequencing, HOR regions as genomic “black holes” have been understudied in...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
8bcbdee0-f5e9-58f2-a5c5-22fa4da083e9
DOI
10.1101/768861
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Rich polymorphic variants of alpha satellite 34mer higher order repeats in hg38 assembly of human chromosome YDOI 10.1101/768861
Classification and monomer-by-monomer annotation of suprachromosomal family 1 alpha satellite higher-order repeats in hg38 human genome assemblySemantic proximity
The variation and evolution of complete human centromeresSemantic proximity
A global view of human centromere variation and evolutionSemantic proximity
Long-read Data Revealed Structural Diversity in Human Centromere SequencesSemantic proximity
Multidimensional variation and population stratification across 8000 complete human centromeresSemantic proximity
Genomic variation within alpha satellite DNA influences centromere location on human chromosomes with metastable epialleles.Semantic proximity
Haplotypes spanning centromeric regions reveal persistence of large blocks of archaic DNASemantic proximity
The variation and evolution of complete human centromeres.Semantic proximity
Large tandem, higher order repeats and regularly dispersed repeat units contribute substantially to divergence between human and chimpanzee Y chromosomes.Semantic proximity
α satellite DNA variation and function of the human centromere.Semantic proximity
Rare k-mers reveal centromere haplogroups underlying human diversity and cancer translocationsSemantic proximity
Complete genomic and epigenetic maps of human centromeresSemantic proximity
Select a neighboring publication to make it the new centre.